If you have OFC appointment and Visa interview back to back days, the best way to go for booking hotel is the one nearest to one of these location, not in between. My recommendation would be to stay closer to OFC center so that you can tackle the first day with no tension.
There are some nice hotels very nearby:
The Raintree Hotel, Anna Salai or
The Residency Towers, Chennai are among them.
If you like to stay closer to the Consulate office where you have the second day interview, there are some nice high-end hotels too. Here are some of the one I know of :
Hotel Palmgrove or
Marriot Courtyard etc.
If you like to stay in a mid-class Hotel, where you don't care about luxury, but just care about some nice neat stay in a/c room and get done with the visa interview, you have some nice cheaper options nearby the US consulate office.
Century Residency ,
Crystal Residency and Shell Residency are among the good ones... Most of them are near the thousand lights area...
Good luck with your interviews... by the way, for the Consulate interview (second day) you can go as early as 1 hrs and most likely you will get the interview done in next 10 mins or so with the new system ... so you can save around 50 min round about in your waiting time in a hotel room..
